San Pedro cactus

Everything about Mescaline

Native Americans have been using mescaline for hundreds of years. Mescaline is a powerful psychedelic alkaloid and it’s found in several species of cactus. Contemporary studies have shown this chemical can give plenty of benefits for psychology and psychiatry.

What is mescaline?


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As mentioned earlier, mescaline is a psychedelic substance present in many cacti who call southern United States and Mexico their home. It is also this part of the world where humans started to use this substance for their spiritual and magical rituals.

Unlike most drugs, mescaline is not physically addictive. With more frequent use, the effects of mescaline become less and less apparent. People who use mescaline are less likely to take consecutive doses.

The effects of mescaline are similar to salt crystals which belong to the phenethylamines family. Some even compare this alkaloid with dopamine.

Mescaline has several uses in spiritual rituals by indigenous groups. It’s also used within the context of leisure. But did you know mescaline is also used in numerous professional activities including psychological therapies and psychiatry.

The first time mescaline was extracted from a cactus for therapeutic purposes was in 1897 by German pharmacologist Arthur Heffter. After studying its effects, Heffter published the results of his research in the scientific journal Naunyn-Schmiedeberg’s Archives of Pharmacology.

After almost 20 years, mescaline was first synthesized by Austrian chemist Ernst Spath in the University of Vienna. Since then, numerous studies have been done to explore the great depth of the effects of mescaline.

Not all cacti species contain mescaline… far from it! It’s only found in some types which grow in Mexico and southern United States. This article will walk you through where to find mescaline, its effects, its recreational uses, and responsible, intelligent use of mescaline.

Which cacti contain mescaline?

Which cacti contain mescaline

Which cacti contain mescaline | Image powered by google

Most of the psychedelic cacti in the world grow around the areas of Mexico and southern United States. Some also come from the continent of Africa. The most popular mescaline-containing cacti are San Pedro and peyote.

  • San Pedro cactus – Evidence points to San Pedro as a traditional cactus used in ancestral rituals. San Pedro is a tall, columnar cactus which traces its ancestry in Peru. It is now propagated and consumed all over the world.

Areas of southern Spain gained a reputation as an ideal area for San Pedro producers because of long hours of sunshine. However, in addition to Peru, San Pedro grows naturally in Chile and Bolivia. It grows at a steady rate of 1 meter per year.

Within the San Pedro cactus variety are other cacti species which contain mescaline such as the Peruvian Torch cactus.

San Pedro

San Pedro | Image powered by google

  • Peyote – Also known as Brandy’s head or drug cactus, peyote was first used more than 5 millennia ago. It was considered as a remedy for various illnesses. In the modern world, it’s used not just by shamans but it’s starting to be recognized as a medicinal plant.

Peyote is also the most studied psychedelic cactus. It also contains other psychedelic alkaloids besides mescaline.

Unlike the San Pedro cactus, Peyote grows short and close t the ground. In the wild, it thrives slowly. It can take 15 years for it to fully mature!

Doňana, another popular psychoactive cactus species, actually doesn’t contain mescaline. There are approximately 70 varieties of psychedelic cacti whose mind-altering effects don’t come from mescaline but originate from other alkaloids.

What are mescaline effects?

It was mentioned earlier that mescaline has psychoactive and hallucinogenic effects. However, these aren’t mescaline’s only effects. Mescaline also has a narcotic and antibiotic effect.

  • Psychological effects of mescaline – This set of effects is the most well-known. People experience sensory alterations and some describe the event as seeing colors which are always changing or they hear sounds which melt together around them.

This is usually euphoric but on the opposite side of the spectrum, some people may suffer through negative emotions due to their negative mindset. Mescaline is also known to trigger nightmares in the unprepared mind.

  • Physical effects of mescaline – Mescaline causes anywhere between mild to moderate nausea and vomiting. Some people report experiencing diarrhea on mescaline too. If taking mescaline for the first time, it’s important to start slow and observe how your body reacts to the substance.
  • Therapeutic effects of mescaline – Mescaline seems to have a potential antibiotic effect. For this reason, people use it to salve their wounds. Because it stimulates vomiting, it’s also use to purge or cleanse the stomach.

Ways to consume mescaline

Ways to consume mescaline

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There are three different ways to consume mescaline: by sucking, ingestion, and injection.

To suck on or eat the flesh of mescaline cactus, it’s important to remove all the spines first, and to cut the flesh open. 6 inches of cactus is enough for one serving.

However, most if not all people cannot stomach the taste of mescaline cactus flesh. Some create mescaline infusions which are a comfortable way to enjoy mescaline.

To create a mescaline infusion, remove the spines and cut the cactus into small pieces. Boil them in water for a few minutes. Drain the liquid and repeat the process with the same pieces of cactus. The liquids which have been boiled and collected are the mescaline solution.

Some people also enjoy mescaline in resin form. Take the aforementioned method a step further. After collecting the batches of liquid, pour them into a glass tray. Place the glass tray inside an over on low heat. The water should evaporate and only the mescaline resin should be left behind. In resin form, mescaline is highly concentrated. Some people ingest the resin directly while some turn it into a powder and put it inside a capsule to consume it.

Tips on taking mescaline

Before you start taking mescaline, there are several things you need to keep in mind.

First, take it slowly. Start with the lowest dose and only work your way up if you want to. While it is not addictive, be careful when taking mescaline because your body is not yet used to its effects.

Second, don’t drive or operate heavy machinery under the influence of mescaline. Don’t perform any tasks requiring concentration. Mescaline will set you on a psychedelic journey and your mind will not be able to focus on the task at hand. This might lead to injury.

Third, don’t take mescaline if you’re in a negative mind set. You’re opening yourself up to the possibility of a powerful bad trip!

And finally, don’t take mescaline if you are pregnant or breastfeeding your kids.

Mescaline is one of the natural chemicals worth experiencing and looking into. Would you like to try mescaline? Order mescaline cactus online today!


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