depression

Psilocybin for Depression

Depression is more than just a state of grief or sadness. This overwhelming state of sorrow affects millions of people worldwide. Unfortunately, most conventional treatments don’t work well and soon enough. Medications for depression take up to two weeks to work. As scientists learn more about magic mushrooms, psilocybin treatment for depression is becoming more likely.

Treating depression with psychedelics defies conventional therapies. However, natural psychedelics such as magic mushrooms have a long tradition of being used to increase cognition, boost the mood, and increase productivity.

Psilocybin for Depression

A new study on using psilocybin for depression, published on October 13th, showed how magic mushrooms reset the brain circuits which play a role in depression.

This study involved 20 participants who were diagnoses with treatment-resistant depression. All 20 participants received two doses of psilocybin: an initial dose of 10mg followed by a 25mg dose after a week.

19 of the 20 study participants underwent brain imaging before and after the psilocybin treatment. This imaging method was used to measure changes in blood flow and the connection between the different brain regions. The patients also filled out questionnaires to enable them to describe their depressive symptoms.

Psilocybin for Depression

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The imaging studies revealed a reduction in the blood flow of areas in the brain responsible for regulating stress and fear. Right after the psilocybin treatment, patients have described their depressive symptoms have decreased.

Several participants have reported feeling a “brain reset” after the treatment. Some even used computer analogies such as having their brains “defragged” similar to a computer hard drive.

Authors of the study believe the results of the study provide better visualization of what goes on in people’s brains after the intense psychedelic effects wear off. The brain connections, for lack of a better word, dissolve during the trip. Afterwards, the person reintegrates and the brain is given a chance to reorient itself with reality and form healthier connections.

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Dr. Robin Carhart-Harris, head of psychedelic research at Imperial College London, claims that the psychoactive component in magic mushrooms – psilocybin – gives the brain the temporary kick start it needs to get out of a depressive state.

This effect is similar to those seen with electroconvulsive therapy but without the painful electric shock.

The results of this study need to be scaled to include a larger population to see if the positive effects can be replicated in more patients. But these findings do show it’s worthy to explore the avenue of whether mushrooms cure depression.

Psilocybin Treatment for Depression

Psilocybin Treatment for Depression

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The study mentioned above is not the first time scientists explored the possibility of shrooms for depression. Several studies have been conducted to establish the link between shrooms and depression.

In December 2016, two psychedelic studies revealed a single dose of psilocybin is capable of immediately lifting anxiety and depression for six months or even longer. The participants were able to end their despair and improve the quality of their lives.

This is a feat which even the best traditional antidepressants can’t do. Unlike magic mushrooms, antidepressants have almost no effect on existential depression of patients diagnosed with terminal cancer. This leads them to feel like their lives are meaningless and they start contemplating suicide.

But how is it like to use psilocybin to treat depression?

Miss A was 25 years old when she first battled serious depression. She is familiar with sadness of course but that was nothing compared to the feeling of new, unexpected pain. “I felt dead. Nothing but blackness,” she said.

Miss A stopped sleeping and soon, depression took its toll on her work as a research analyst. Oftentimes she found herself crying in toilets where feelings of hopelessness would envelope her.

Her bout of depression lasted a year but even when it lifted, she still felt low. Like millions of depressive patients all over the world, Miss A was prescribed with SSRI, a form of anti-depressants. SSRI helped her stop crying but they also made her feel numb.

Unfortunately, the positive effects didn’t last long. Despite taking higher doses of SSRI, her depression took a turn for the worse and deepened.

“I was thinking obsessively and negatively, constantly,” she claimed. Miss A even tried therapy but the pain was persistent.

Who knew visiting internet forums would give Miss A the answer she needed?

Microdosing Psilocybin for Depression

Microdosing Psilocybin for Depression

Miss A found an article about microdosing, the practice of taking barely-perceptible amounts of psilocybin to relieve depression.

Despite not touching magic mushrooms for years, Sue found herself grinding magic mushrooms. On day one, she started with a quarter of a teaspoon.

The effects were minimal. Day 1 brought Miss A additional energy but nothing more. She had the energy to stay awake until the afternoon – an unusual feat for her.

It was the effect on Day 2 that really amazed Miss A. “My obsessive negative thinking literally just stopped. Even when I tried to find the negative thoughts, they weren’t there; they had just disappeared,” she recalled.

These effects are not unique to Miss A. Patients suffering from depression are able to feel functional almost as soon as they start microdosing. This isn’t about taking psychedelics for pleasure anymore. This is about taking nature’s gift, psilocybin, to treat depression and save lives.

Where Does this Leave Psilocybin Mushrooms for Depression?

Plenty of studies need to be done before pharmaceuticals start synthesizing and marketing psilocybin for depression. Luckily, magic truffles are available online. These psychedelic truffles contain amounts of psilocybin for depression treatment.

However this leaves the question: is it safe to microdose psilocybin mushrooms for depression? Microdosing magic mushrooms doesn’t have major undesirable effects or even addictive properties. Those alone puts microdosing psilocybin for depression a step above traditional antidepressants.

You can use magic mushrooms to elevate your mood and improve your days without having to worry about any negative effects.

You can check this guide to microdosing psilocybin for depression.

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